Development and validation of stability indicating the RP-HPLC method for the estimation of related compounds of guaifenesin in pharmaceutical dosage forms
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Development and validation of stability indicating the RP-HPLC method for the estimation of related compounds of guaifenesin in pharmaceutical dosage forms
AIM AND BACKGROUND A stability-indicating gradient reverse phase liquid chromatographic (RP-LC) method was developed for the quantitative determination of related substances of guaifenesin in pharmaceutical formulations. MATERIALS AND METHODS The baseline separation for guaifenesin and all impurities was achieved by utilizing a Water Symmetry C18 (150 mm × 4.6 mm) 5 μm column particle size an...
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ژورنال
عنوان ژورنال: Pharmaceutical Methods
سال: 2011
ISSN: 2229-4708
DOI: 10.4103/2229-4708.93391